Bianzhen is a genetic testing product that focuses on precise molecular diagnosis of epilepsy. It includes two series: (1) Panel 2000× package, (2) WES Plus package. Its research and development is based on independent research and development database, using international authoritative data , Combined with second-generation sequencing technology, comprehensively screen epilepsy-related genes, provide genetic basis for the clear diagnosis of epilepsy risk populations and patients with epilepsy, and establish a new model of individualized medical treatment.

Among them, the Panel 2000× package can detect 876 epilepsy-related genes, 23 epilepsy hotspot copy number variants (CNVs), mosaics, and mitochondrial genomes. The average sequencing depth is up to 2000×, and the average sequencing depth of mitochondrial genomes is 10,000×. Chimeric mutations with a synergy rate as low as 1%.

The WES Plus package comprehensively covers all exons, 23 epilepsy-related hotspot CNVs, mitochondrial genomes, and includes the clinically significant mutation sites in the non-exon regions included in the latest ClinVar database. Covers all pathogenic genes related to epilepsy, with a coverage area of up to 43.2Mb, a sequencing data volume of 20G, an average sequencing depth of 200×-300×, and a mitochondrial genome sequencing depth of up to 10,000×, thereby significantly improving the detection rate of mutations .